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Publications en 2018

Peer-reviewed publications in International Journals

[2-U L18]

miRNA-135b Contributes to Triple Negative Breast Cancer Molecular Heterogeneity: Different Expression Profile in Basal-like Versus non-Basal-like Phenotypes

Paolo Uva, Paolo Cossu-Rocca, Federica Loi, Giovanna Pira, Luciano Murgia, Sandra Orrù, Matteo Floris, Maria Rosaria Muroni, Francesca Sanges, Ciriaco Carru, Andrea Angius, Maria Rosaria De Miglio

International Journal of Medical Sciences - march 2018 doi: 10.7150/ijms.23402

Publications en 2017

Peer-reviewed publications in International Journals

[2-SOI17]

Overexpression of the Cytokine BAFF and Autoimmunity Risk

Maristella Steri, Valeria Orrú, Maria Laura Idda, Maristella Pitzalis, Mauro Pala, Ilenia Zara, Sidore Carlo, Valeria Faa, Matteo Floris, ..., Roberto Cusano, Gianmauro Cuccuru, . ..., Francesco Cucca

The New England Journal of Medicine pages 1615-1626 vol. 376 - april 2017 doi: 10.1056/NEJMoa1610528

Publications en 2016

Peer-reviewed publications in International Journals

[2-FRM16]

Fragment Prioritization on a Large Mutagenicity Dataset

Matteo Floris, Giuseppa Raitano, Ricardo Medda, Emilio Benfenati

Molecular Informatics - 2016 doi: 10.1002/minf.201600133

Publications en 2015

Peer-reviewed publications in International Journals

[2-ZC.15]

Height-reducing variants and selection for short stature in Sardinia

Magdalena Zoledziewska, Sidore Carlo, ..., Matteo Floris, . ..., David Schlessinger, Francesco Cucca

Nature Genetics pages 1352--6 vol. 47 num. 11 - 2015 doi: 10.1038/ng.3403

Peer-reviewed publications in national events

[5-CSP15]

Rational design of new candidate compounds for multiple sclerosis treatment based on analysis of biological targets identified through genome wide association studies in Sardinia

Francesco Cucca, Maristella Steri, Maristella Pitzalis, Magdalena Zoledziewska, Valeria Orrú, Ilenia Zara, Eleonora Porcu, Antonella Mulas, Francesca Deidda, Isadora Asunis, Sole Gabriella, Francesca Virdis, Raffaele Murru, Michael Whalen, Fabio Busonero, Andrea Maschio, Andrea Angius, Christopher M. S. Jones, Eleonora Cocco, Gianna Costa, Cristina Mancosu, Jessica Frau, Lorena Lorefice, Giada Fenu, Giancarlo Coghe, Marta Melis, Sonia Sanna, Fausto Poddie, Maria Laura Idda, Laura Morelli, Gabriele Farina, Piero Cossu, Maurizio Melis, Paola Ferrigno, Carlo Sidore, Giulio Rosati, Sandra DAlfonso, Valeria Faa, Stefania Olla, Mauro Pala, Gonçalo R. Abecasis, Alessandra Meloni, Matteo Floris, Edoardo Fiorillo, Maria Giovanna Marrosu, Serena Sanna

FISM (Fondazione Italiana Sclerosi Multipla) Meeting 2015 - 2015

Publications en 2014

Peer-reviewed publications in International Journals

[2-GGF14]

An alternative QSAR-based approach for predicting the bioconcentration factor for regulatory purposes

Andrea Gissi, Domenico Gadaleta, Matteo Floris, Stefania Olla, Angelo Carotti, Ettore Novellino, Emilio Benfenati, Orazio Nicolotti

Altex pages 23-36 vol. 31 num. 1 - 2014

[2-PAF14]

BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT

Ignazio Piras, Andrea Angius, Matteo Floris, Maria Grazia Roncarolo, Alessandro Bulfone, Rosa Bacchetta

Bone marrow transplantation Nature Publishing Group - 2014 doi: 10.1038/bmt.2014.177

[2-FMM14]

A generalizable definition of chemical similarity for read-across

Matteo Floris, Alberto Manganaro, Ricardo Medda, Giuseppe Felice Mangiatordi, Orazio Nicolotti, Emilio Benfenati

Journal of Chemoinformatics - 2014 doi: 10.1186/s13321-014-0039-1

Peer-reviewed publications in national events

[5-CSP14]

Rational design of new candidate compounds for multiple sclerosis treatment based on analysis of biological targets identified through genome wide association studies in Sardinia

FISM (Fondazione Italiana Sclerosi Multipla) Meeting 2014 - 2014

Publications en 2013

Peer-reviewed publications in International Journals

[2-FCO13]

Overlapping syndromes in laminopathies: a meta-analysis of the reported literature

Matteo Floris, Nicola Carboni, Stefania Olla, Anna Mateddu, Maria Giovanna Marrosu, Eleonora Cocco

Acta Myologica Pacini editore vol. 32 num. 1 - 2013

[2-FCO13]

Overlapping syndromes in laminopathies: a meta-analysis of the reported literature

Matteo Floris, Nicola Carboni, Stefania Olla, Anna Mateddu, Maria Giovanna Marrosu, Eleonora Cocco

Acta Myologica Pacini editore vol. 32 num. 1 - 2013

[2-FFS13]

MMsDusty: an Alternative InChI‐Based Tool to Minimize Chemical Redundancy

Marco Fanton, Matteo Floris, Davide Sabbadin, Ricardo Medda, Andrea Cristiani, Stefania Olla, Alessandro Bulfone

Molecular Informatics WILEY‐VCH Verlag pages 681-684 vol. 32 num. 8 - 2013 doi: 10.1002/minf.201300061

[2-FSC13]

Implementing the “Best Template Searching” tool into Adenosiland platform

Matteo Floris, Davide Sabbadin, Antonella Ciancetta, Ricardo Medda, Stefano Moro

In Silico Pharmacology Springer pages 25 vol. 1 num. 1 - 2013 doi: 10.1186/2193-9616-1-25

[2-OSC13]

Genetic Variants Regulating Immune Cell Levels in Health and Disease

Valeria Orrú, Maristella Steri, Sidore Carlo, Francesca Virdis, Mariano Dei, Sandra Lai, Magdalena Zoledziewska, Fabio Busonero, Antonella Mulas, Matteo Floris, Wieslawa Mentzen, Silvana Urru, michele marongiu, Stefania Olla, MG Piras, Lobina M., Andrea Maschio, Maristella Pitzalis, Maria Francesca Urru, Marco Marcelli, Roberto Cusano, Francesca Deidda, Manuela Oppo, Rosella Pilu, Frederic Reinier, Riccardo Berutti, Luca Pireddu, Ilenia Zara, Eleonora Porcu, Alan Kwong , Christine Brennan , Brendan Tarrier, Hyun Kang , Robert Lyons, Sergio Uzzau, Rossano Atzeni, Maria Valentini, Firinu D., Lidia Leoni, Gianluca Rotta, Silvia Naitza, Andrea Angius, Mauro Congia, Michael Whalen, Christopher M. S. Jones, David Schlessinger, Gonçalo R. Abecasis, Edoardo Fiorillo, Serena Sanna, Francesco Cucca

Cell Elsevier Inc pages 242-256 vol. 155 num. 1 - september 2013 doi: 10.1016/j.cell.2013.08.041

Peer-reviewed publications in international events

[4-VEF13]

Drug repositioning and computational analysis for myelin disease regenerative therapies

Caterina Veroni, Cecilia Eleuteri, Matteo Floris, Stefania Olla, Marco Salvetti, Cristina Agresti, Renato Umeton

Ectrims 2013 SAGE PUBLICATIONS LTD - 2013

Publications en 2012

Peer-reviewed publications in International Journals

[2-CSP12]

HLA-DRB1-DQB1 Haplotypes Confer Susceptibility and Resistance to Multiple Sclerosis in Sardinia

Eleonora Cocco, Claudia Sardu, Enrico Pieroni, Maria Valentini, Raffaele Murru, Gianna Costa, Stefania Tranquilli, Jessica Frau, Giancarlo Coghe, Nicola Carboni, Matteo Floris, Paolo Contu, Maria Giovanna Marrosu

PLoS ONE - 2012 doi: 10.1371/journal.pone.0033972

[2-FSM12]

Adenosiland: walking through adenosine receptors landscape

Matteo Floris, Davide Sabbadin, Ricardo Medda, Alessandro Bulfone, Stefano Moro

European Journal of Medicinal Chemistry ScienceDirect - october 2012 doi: 10.1016/j.ejmech.2012.10.022

Various talks, works and publications

[5-FLO12]

Dalla genomica, alla struttura delle proteine, al drug design

Matteo Floris

Collana seminari interni 2012 pages 1 num. 20120208 - february 2012

Publications en 2011

Peer-reviewed publications in International Journals

[2-CFM11]

Aberrant splicing in lmna gene caused by a novel mutation on the polypyrimidine tract of the intron 5

Nicola Carboni, Matteo Floris, Anna Mateddu, Maurizio Porcu, Giovanni Marrosu, Elisabetta Solla, Eleonora Cocco, Marco Mura, Stefano Marini, Rachele Piras, R Aste, Maria Giovanna Marrosu

Muscle & Nerve - 2011 doi: 10.1002/mus.21937

[2-FDG11]

MAISTAS: a tool for automatic structural evaluation of alternative splicing products

Matteo Floris, Raimondo Domenico, Leoni Guido, Massimiliano Orsini, Paolo Marcatili, Anna Tramontano

Bioinformatics Oxford journals - 2011 doi: 10.1093/bioinformatics/btr198

[2-CBC11]

ClickMD: an intuitive web-oriented molecular dynamics platform

Andrea Cristiani, Nicola Brisotto, Fabian Chatwin Cedrati, Matteo Floris, Leonardo Scapozza, Stefano Moro

Future Medicinal Chemistry Future Science - 2011 doi: 10.4155/fmc.11.59

[2-FFM11]

Swimming into peptidomimetic chemical space using pepMMsMIMIC

Matteo Floris, Marco Fanton, Joel Pierre Masciocchi, Stefano Moro

Nucleic Acid Research Database Issue - 2011 doi: 10.1093/nar/gkr287

[2-FM11]

Mimicking peptides... in silico

Matteo Floris, Stefano Moro

Molecular informatics Wiley - 2011
issn: 1868-1751 doi: 10.1002/minf.201100093

[2-VTM11]

A A386G biallelic GPIbα gene mutation with anomalous behavior: a new mechanism suggested for Bernard-Soulier syndrome pathogenesis

Silvia Vettore, Fabiana Tezza, Alessandro Malara, Fabrizio Vianello, Alessandro Pecci, Raffaella Scandellari, Matteo Floris, Alessandra Balduini, Fabrizio Fabris

Haematologica Ferrata Storti Foundation - 2011 doi: 10.3324/haematol.2010.039008

Various talks, works and publications

[6-FLO11]

Una piattaforma computazionale per lo screening di potenziali peptidomimetici a partire da grandi librerie chimiche (Personal communication, Convegno La chimica in Sardegna, Porto Conte)

Matteo Floris

- 2011

[6-FLO11]

"Chemoinformatics on an island", 1° Computer driven drug discovery meeting, L'Aquila

Matteo Floris

Personal communication - - november 2011

[6-MFU11]

Epigenetic regulation of microRNAs during embryonic stem cell differentiation

Wieslawa Mentzen, Matteo Floris, Paolo Uva

Poster presentation at the ISMB/ECCB 2011, Vienna, 17-19 July 2011 - july 2011

[3-FC11]

Nuovi strumenti computazionali per la ricerca farmaceutica

Matteo Floris, Andrea Cristiani

La chimica e l'industria - june 2011

[6-FLO11]

"Swimming into peptidomimetics drug space", Convegno nuove prospettive in chimica farmaceutica, Trieste

Matteo Floris

Personal communication - - may 2011

[6-FLO11]

From genomics to in silico pharmacology (Personal communication, BeMM symposium 2011, University of Rome “La Sapienza”)

Matteo Floris

Personal communication - - january 2011

Thesis and academic qualification

[9-FLO11]

"Implicazioni funzionali, strutturali e farmacogenomiche dello splicing alternativo: approcci computazionali.", PhD thesis

Matteo Floris

University of Rome - march 2011

Publications en 2010

Peer-reviewed publications in International Journals

[2-MPF10]

Support vector machine (svm) as alternative tool to assign acute aquatic toxicity warning labels to chemicals

L Michielan, Luca Pireddu, Matteo Floris, Stefano Moro

Molecular Informatics vol. 29:1-2 - 2010 doi: 10.1002/minf.200900005

[2-FCV10]

A novel mutation in Lamin A/C gene: phenotype and consequences on the protein structure and flexibility

Matteo Floris, Nicola Carboni, Maria Valentini, Giovanni Marrosu, Eleonora Cocco, Maria Antonietta Maioli, Elisabetta Solla, Anna Mateddu, Marco Mura, Maria Giovanna Marrosu

SRX Biology SRX - 2010 doi: 10.3814/2010/301679

Various talks, works and publications

[6-FMU10]

Connections between epigenetics and microRNAs during embryonic stem cell differentiation

Matteo Floris, Wieslawa Mentzen, Paolo Uva

Poster at the 2nd Next-Generation Sequencing workshop, Bari, 6-8 October 2010 - october 2010

Publications en 2009

Peer-reviewed publications in International Journals

[2-MFD09]

Dissecting the dynamics of dysregulation of cellular processes in mouse mammary gland tumor

Wieslawa Mentzen, Matteo Floris, Alberto de la Fuente

BMC Genomics vol. 10 num. 601 - 2009 doi: 10.1186/1471-2164-10-601

[2-MFF09]

Mmsinc: a large-scale chemoinformatics database

Joel Pierre Masciocchi, Gianfranco Frau, Marco Fanton, Mattia Sturlese, Matteo Floris, Luca Pireddu, Piergiorgio Palla, Fabian Chatwin Cedrati, Patricia Rodriguez-Tomé, Stefano Moro

Nucleic Acid Research Database Issue Oxford University Press pages 284-290 num. 37 - january 2009 doi: 10.1093/nar/gkn727

Various talks, works and publications

[6-FVC09]

Modeling effects of a novel mutation in the coiled-coil structure of lmna gene

Matteo Floris, Maria Valentini, Nicola Carboni, Eleonora Cocco

Poster presented at the ISMB/ECCB conference, June 27 - July 2, Stockholm, Sweden - 2009

[6-PMF09]

Fingerprint-based detection of high acute aquatic toxicity

Luca Pireddu, L Michielan, Matteo Floris, Patricia Rodriguez-Tomé, Stefano Moro

poster - n German Conference on Chemoinformatics, CIC- Workshop 2009 - november 2009

[6-MPM09]

MMsPred: a bioactivity and toxicology predictive system

Joel Pierre Masciocchi, Luca Pireddu, Ricardo Medda, Piergiorgio Palla, Matteo Floris, Luca Pani, Patricia Rodriguez-Tomé

Poster - in Predictive ADMET Workshop, Oxford University, Oxford, UK - july 2009

[6-MFD09]

Dissecting the dynamics of dysregulation of cellular processes in mouse mammary gland tumor

Wieslawa Mentzen, Matteo Floris, Alberto de la Fuente

Poster presented at Intelligent Systems for Molecular Biology (ISMB) - Stockholm, Sweden - june 2009

[6-MFF09]

MMsINC®: a large-scale chemoinformatics database system

Joel Pierre Masciocchi, Matteo Floris, Marco Fanton, Gianfranco Frau, Mattia Sturlese, Piergiorgio Palla, Fabian Chatwin Cedrati, Luca Pireddu, Ricardo Medda, Patricia Rodriguez-Tomé, Stefano Moro

Poster - Société Française de Chémoinformatique, Journées 2009, Montpellier, France - june 2009

Publications en 2008

Peer-reviewed publications in International Journals

[2-FOA08]

Splice-mediated variants of proteins (splivap) - data and characterization of changes in signatures among protein isoforms due to alternative splicing

Matteo Floris, Massimiliano Orsini, Thanaraj Thangavel Alphonse

BMC Genomics vol. 9 num. 453 - 2008

Peer-reviewed publications in international events

[4-FFF08]

MMsINC: A new public large-scale chemoinformatics database system

Marco Fanton, Matteo Floris, Gianfranco Frau, Joel Pierre Masciocchi, Mattia Sturlese, Piergiorgio Palla, Fabian Chatwin Cedrati, Patricia Rodriguez-Tomé, Stefano Moro

BIOTECHNO 2008 Proceedings IEEE Computer Society Press nternational Conference on Biocomputation, Bioinformatics, and Biomedical Technologies, pages 64-69 num. 2008 IARIA - 2008

[4-FFM08]

Andhira: from biodiversity to chemo diversity – the database of Sardinian endemic plants and their molecules

Matteo Floris, Gianfranco Frau, Joel Pierre Masciocchi, Mocci Giuseppe, Piergiorgio Palla, Vera Uras, Patricia Rodriguez-Tomé

7th Joint Meeting of GA, AFERP, ASP, PSE & SIF - Athens, Greece, August 3-8, 2008 Planta Medica - PLANTA MED vol. 74 - 2008 doi: 10.1055/s-0028-1083894

Various talks, works and publications

[6-MFD08]

Network oncology: analysis of cancer gene expression in the context of protein interaction networks and mirna target motifs

Wieslawa Mentzen, Matteo Floris, Alberto de la Fuente

Poster presented at ECCB 2008, Cagliari, Italy, September 22-25 - 2008

[6-MFD08]

Network oncology: analysis of cancer gene expression in the context of protein interaction networks and mirna target motifs

Wieslawa Mentzen, Matteo Floris, Alberto de la Fuente

Poster presented at the International Conference on Systems Biology (ISMB), 2008, Goteborg, Sweden - 2008

[6-MFF08]

MMsINC®: a new public large-scale chemoinformatics database system,

Joel Pierre Masciocchi, Marco Fanton, Matteo Floris, Gianfranco Frau, Mattia Sturlese, Piergiorgio Palla, Fabian Chatwin Cedrati, Stefano Moro, Patricia Rodriguez-Tomé

Poster - in Ecole d'été de Strasbourg en Chemoinformatique, Obernai, France - june 2008

Publications en 2007

Peer-reviewed publications in International Journals

[2-CDD07]

The meps server for identifying protein conformational epitopes.

Tiziana Castrignano, De Meo Paolo D'Onorio, Carrabino Danilo, Massimiliano Orsini, Matteo Floris, Anna Tramontano

BMC Bioinformatics pages S6 vol. 8 Suppl 1 - 2007

[2-DMN07]

The mepsmap server. mapping epitopes on protein surface: mining annotated proteins.

Carrabino D, Paolo DÓnorio De Meo, Sartori N, Tiziana Castrignano, Massimiliano Orsini, Matteo Floris, Anna Tramontano

IEEE Transactions on Nanobioscience pages 155--161 vol. 6 num. 2 - 2007

[2-CMC07]

The meps server for identifying protein conformational epitopes

Tiziana Castrignano, Paolo DÓnorio De Meo, Danilo Carrabino, Massimiliano Orsini, Matteo Floris, Anna Tramontano

BMC Bioinformatics vol. 8 num. (Suppl 1): - 2007

[2-CMC07]

The meps server for identifying protein conformational epitopes

Tiziana Castrignano, Paolo DÓnorio De Meo, Danilo Carrabino, Massimiliano Orsini, Matteo Floris, Anna Tramontano

BMC Bioinformatics vol. 8 num. (Suppl 1): - 2007

Various talks, works and publications

[6-OFT07]

Splivap: a data resource on splice-mediated changes in isoform protein sequences

Massimiliano Orsini, Matteo Floris, Anna Tramontano, Thanaraj Thangavel Alphonse

Poster presented at the 15th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB) & 6th European Conference on Computational Biology (ECCB), Vienna (Austria) - 2007

[6-BCF07]

Andhìra, a database for bioactive molecules of the sardinian endemic flora (ii)

Giuliana Brunetti, Sergio Contrino, Matteo Floris, Gianfranco Frau, Joel Pierre Masciocchi, Patricia Rodriguez-Tomé

Poster - Future Trends in Phytochemistry - A Young Scientists Symposium - Gargnano, Italy, no. P30 - june 2007

Publications en 2006

Various talks, works and publications

[6-CMD06]

The meps server for identifying protein conformational epitopes

Tiziana Castrignano, Paolo DÓnorio De Meo, Carrabino D, Massimiliano Orsini, Matteo Floris, Anna Tramontano

Presentation at the NETTAB'06 workshop, Pula, 10-13 July 2006 - july 2006

54 publications Download the selection